학술논문
BASIC AND CLINICAL EVALUATION OF SULFOBENZYLPENICILLIN / Sulfobenzylpenicillinの基礎的および臨床的検討
Document Type
Journal Article
Author
Source
CHEMOTHERAPY. 1971, 19(8):1023
Subject
Language
Japanese
ISSN
0009-3165
1884-5894
1884-5894
Abstract
Antibacterial spectrum of sulfobenzylpenicillin (SB-PC) was about equal to that of carbenicillin (CB-PC). Against E. coli, SB-PC was more active than CB-PC. MIC of SB-PC in which a distribution peak of 53 comparatively new clinical isolates of Pseudomonas aeruginosa was lower than that of CB-PC.Degradation of SB-PC and CB-PC with β-lactamase was very low as compared with that of ampicillin and benzylpenicillin.Ten patients with chronic prostatitis, chronic cystitis, acute and chronic pyelonephritis and acute prostatocystitis were treated with SB-PC. Five cases received 1 to 2g daily and the other 5 cases received 8-13 g daily. Results were good in all the cases.