학술논문
Ectopic pulmonary calcification after parathyroidectomy in multiple myeloma / 副甲状腺切除後に異所性肺石灰化を認めた多発性骨髄腫
Document Type
Journal Article
Author
Chika SAKAKI; Daisuke INOUE; Hidehiro ITONAGA; Hikaru SAKAMOTO; Hiroshi MUKAE; Junya FUKUOKA; Kazuko YAMAMOTO; Koji ANDO; Machiko FUJIOKA; Makiko HOURAI; Masahiro ICHINOSE; Masataka TAGUCHI; Miki HASHIMOTO; Moe TANAKA; Shinya SATO; Takafumi FURUMOTO; Tomoko HATA; Yasushi MIYAZAKI; Yasushi SAWAYAMA; Yoshiaki ZAIZEN; Yoshitaka IMAIZUMI; 一瀬 将広; 井上 大輔; 今泉 芳孝; 佐藤 信也; 古本 嵩文; 坂本 光; 安東 恒史; 宮﨑 泰司; 山本 和子; 榊 智佳; 橋本 美紀; 波多 智子; 澤山 靖; 田中 萌; 田口 正剛; 福岡 順也; 糸永 英弘; 蓬莱 真喜子; 藤岡 真知子; 財前 圭晃; 迎 寛
Source
臨床血液 / Rinsho Ketsueki. 2019, 60(7):785
Subject
Language
Japanese
ISSN
0485-1439
1882-0824
1882-0824
Abstract
Ectopic soft tissue calcification (ESTC), a rare clinical condition, causes tissue and organ damage. It is associated with chronic renal failure, hyperparathyroidism, and malignant neoplasms, including multiple myeloma, and it is reportedly resistant to treatment. Here, we present the case of a 71-year-old male with multiple myeloma who had rapid ESTC in the lung. He had developed hypoparathyroidism secondary to thyroidectomy. During the course of our observation, he rapidly developed ectopic pulmonary calcification approximately 2 weeks after acquiring an infection. There was no evidence of further progression of multiple myeloma after the onset of ESTC, and treatment with ferric citrate hydrate and precipitated calcium resulted in immediate improvement of his pulmonary signs. We recommend cautious monitoring for patients with multiple myeloma and hypoparathyroidism to detect the onset of ectopic calcification. In addition, low blood phosphorus levels should be effectively treated.