학술논문

True state and outcome of diffuse intrinsic pontine glioma in Japan: a retrospective questionnaire survey to evaluate the clinical factors affecting the prognosis of rare pediatric brain tumors by the Study Group of 'Nationwide Multicenter Studies to establish Standard Treatment for Childhood Brain Tumors' in the Japan Children’s Cancer Group (JCCG) financed through a grant from the Japan Agency for Medical Research and Development (AMED) / 日本におけるびまん性橋膠腫(diffuse intrinsic pontine glioma: DIPG)の治療実態とその成績:JCCG(日本小児がん研究グループ)/AMED(日本医療研究開発機構研究委託費)原班(小児脳腫瘍に対する多施設共同研究による治療開発)による稀少小児脳腫瘍の予後に関する臨床的要因を検討する後方視的調査研究結果
Document Type
Journal Article
Source
小児の脳神経 / Nervous System in Children. 2022, 47(3):279
Subject
chemotherapy
diffuse intrinsic pontine glioma
outcome
radiation
treatment
Language
Japanese
ISSN
0387-8023
2435-824X
Abstract
Results: Biopsy or partial resection was performed in about 20% of patients. Almost all patients received radiotherapy, and three-fourths received chemotherapy mainly using temozolomide. Median overall survival (OS) was 338 days. OS showed no significant differences between 1) photon and proton radiotherapy, 2) with or without chemotherapy, and 3) chemotherapeutic agents.