학술논문

Metastasizing Pleomorphic Adenoma Diagnosed via Endoscopic Ultrasound with Bronchoscope-guided Fine-needle Aspiration / 多形腺腫摘出10年後に認められた肺転移に対してEUS-B-FNAで診断した1例
Document Type
Journal Article
Source
気管支学 / The Journal of the Japan Society for Respiratory Endoscopy. 2023, 45(6):425
Subject
Endoscopic ultrasound with bronchoscope-guided fine-needle aspiration
Metastatic lung tumor
Pleomorphic adenoma
多形腺腫
経食道的気管支鏡下穿刺吸引生検法
肺転移
Language
Japanese
ISSN
0287-2137
2186-0149
Abstract
Background. Endoscopic ultrasound bronchoscope-guided fine-needle aspiration (EUS-B-FNA) is useful for diagnosing mediastinal lesions. Case. A 70-year-old woman underwent right submandibular adenectomy for a submandibular gland tumor at our hospital in October 2009, and the surgical pathology revealed pleomorphic adenoma. In July 2019, multiple pulmonary nodules were found incidentally, and a computed tomography-guided needle biopsy or surgical lung biopsy was recommended, as bronchoscopy was difficult owing to nodule localization; however, the patient refused treatment. In March 2023, at 84 years old, the patient was referred to our hospital for palliative radiation after the discovery of a metastatic bone tumor at the cervical spine (C6) and multiple enlarged pulmonary nodules. Endobronchial ultrasonography with a guide sheath (EBUS-GS) was performed on the central lesion with a positive air bronchus sign in the left upper lobe (B1+2), but the rapid on-site cytologic evaluation was negative. Consequently, we performed EUS-B-FNA, taking samples of the pulmonary nodules through the esophagus. The pathological findings of the EUS-B-FNA tissue specimen were comparable to those of the 2009 pleomorphic adenoma surgical specimen, so the patient was diagnosed with lung metastases of pleomorphic adenoma. Conclusion. EUS-B-FNA proved suitable for diagnosing lung metastases of pleomorphic adenoma.