학술논문
Comparison of the OPTIVUS-Complex PCI Multivessel Cohort With the Historical CREDO-Kyoto Registry Cohort-3
Document Type
Journal Article
Author
Akiyoshi Miyazawa; Hideki Okayama; Hidekuni Kirigaya; Hiroki Sakamoto; Hiroki Shiomi; Hiroki Watanabe; Hiroshi Ueda; Jun Kuribara; Kazushige Kadota; Kengo Tanabe; Kenji Ando; Kenji Nakatsuma; Kensho Matsuda; Kiyoshi Hibi; Kiyotaka Shimamura; Ko Yamamoto; Koh Ono; Kohei Yoneda; Kota Komiyama; Kyohei Yamaji; Masanobu Ohya; Masataka Shigetoshi; Mitsuru Abe; Naotaka Okamoto; Ryoji Taniguchi; Satoru Mitomo; Satoru Sasaki; Satoru Suwa; Shojiro Tatsushima; Sunao Nakamura; Takenori Domei; Takeshi Kimura; Takeshi Morimoto; Umihiko Kaneko; Yohei Takayama; Yuji Nishimoto; Yuta Imai; on behalf of the OPTIVUS-Complex PCI Investigators
Source
Circulation Journal. 2023, 87(11):1689
Subject
Language
English
ISSN
1346-9843
1347-4820
1347-4820
Abstract
Methods and Results: The OPTIVUS-Complex PCI study multivessel cohort was a prospective multicenter single-arm study enrolling 1,021 patients undergoing multivessel PCI including the left anterior descending coronary artery using IVUS aiming to meet the prespecified criteria for optimal stent expansion. We conducted propensity score matching analyses between the OPTIVUS group and historical PCI or CABG control groups from the CREDO-Kyoto registry cohort-3 (1,565 and 899 patients) fulfilling the inclusion criteria for this study. The primary endpoint was a composite of death, myocardial infarction, stroke, or any coronary revascularization. In the propensity score-matched cohort (OPTIVUS vs. historical PCI control: 926 patients in each group; OPTIVUS vs. historical CABG control: 436 patients in each group), the cumulative 1-year incidence of the primary endpoint was significantly lower in the OPTIVUS group than in the historical PCI control group (10.4% vs. 23.3%; log-rank P<0.001) or the historical CABG control group (11.8% vs. 16.5%; log-rank P=0.02).