학술논문
Systemic therapy for pancreatic neuroendocrine tumors / 膵NENの薬物療法
Document Type
Journal Article
Author
Source
膵臓 / Suizo. 2023, 38(6):390
Subject
Language
Japanese
ISSN
0913-0071
1881-2805
1881-2805
Abstract
Systemic therapy for pancreatic NEN differs for pancreatic neuroendocrine tumor (NET) and pancreatic neuroendocrine carcinoma (NEC). For pancreatic NETs, treatment purpose differs between hormonal symptom control or tumor growth suppression. Somatostatin analogues are mainly for hormonal symptom control. Somatostatin analogues, molecular target agents, and cytotoxic agents are for tumor growth suppression. Proper use is guided by the treatment selection MAP for pancreatic NETs. In addition, radionuclide-labeled peptide therapy is now available in Japan, and timing of introduction is also important. Platinum-based chemotherapy is standard treatment for pancreatic NEC. Various treatments are available for pancreatic NEN, so a multidisciplinary approach that makes proper use of these treatments is required.