부산대학교 도서관

We report a case of primary endometrial squamous cell carcinoma, which was suspected preoperatively. A 65year-old woman (gravida three, para zero), with a two-year history of postmenopausal genital bleeding was referred to our department, with suspected endometrial cancer. A two cm endometrial mass was detected on vaginal ultrasonogram. Both endometrial cytology and biopsy indicated a squamous cell carcinoma. Although the endometrial tumor was proximal to the internal uterine os, no obvious cervical lesion was found during speculum examination and on imaging studies. Considering the endometrial squamous cell carcinoma diagnosis, we performed semi-radical hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphadenectomy. The resected uterus showed a protruding lesion from the isthmus. Squamous cell carcinoma with keratinization, lacking adenocarcinomatous components, was diagnosed. There was no continuity between the carcinoma and cervical epithelium. Further, no other cervical lesion was noted.The final diagnosis was a squamous cell carcinoma of the uterine corpus, pT1a. HPV was not detected via immunohistochemistry. No additional postoperative treatment was needed. Furthermore, recurrence was not noted during 15 months follow-up period. Endometrial squamous cell carcinoma is a rare disease; therefore, it is necessary to gather more cases to establish or standardize its diagnosis and treatment. [Adv Obstet Gynecol, 75(3) :372-377, 2023 (R5.8)]