학술논문

Marked hypoglycemia during perioperative period in patient with gastric cancer and solitary fibrous tumor / 胃癌周術期に低血糖症状が顕著となった孤立性線維性胸膜腫瘍の1例
Document Type
Journal Article
Source
日本呼吸器外科学会雑誌 / The Journal of the Japanese Association for Chest Surgery. 2022, 36(7):827
Subject
insulin-like growth factor-II
non-islet cell tumor hypoglycemia
solitary fibrous tumor
インスリン様成長因子II
孤立性線維性腫瘍
非膵島細胞腫瘍性低血糖
Language
Japanese
ISSN
0919-0945
1881-4158
Abstract
A solitary fibrous tumor (SFT) rarely causes hypoglycemia. We report a patient with gastric cancer and an SFT, in whom marked hypoglycemia developed during the perioperative period. Chest radiograph findings showed an abnormal shadow in the left lower lung field of an 80-year-old man, which was diagnosed as an SFT based on bronchoscopy biopsy results. Additionally, gastric cancer was detected during that time; thus, a total gastrectomy was performed before treatment for the tumor. Mild fasting hypoglycemia was observed prior to the gastrectomy and it remained postoperatively, although it was asymptomatic and could be controlled with diet therapy. After discharge, the patient was brought back to the hospital due to unconsciousness and his fasting blood glucose level was extremely low. This was considered to be a symptom associated with the SFT, and resection of the tumor was performed. Following surgery, hypoglycemia was found to have resolved. High-molecular-weight insulin-like growth factor II (IGF-II) was detected in preoperative serum, and hypoglycemia as a tumor-associated symptom was diagnosed. It should be noted that hypoglycemia due to an SFT can be exacerbated during the course of the disease.