학술논문

Regulation of Cell Dynamics by Cell Surface Modification / 細胞膜修飾による細胞挙動の制御
Document Type
Journal Article
Source
オレオサイエンス / Oleoscience. 2023, 23(5):259
Subject
cell surface modification
cell therapy
mesenchymal stem cells
pharmacokinetics
Language
Japanese
ISSN
1345-8949
2187-3461
Abstract
In this paper, we first give an overview of the three approved cell preparations and cell kinetics, then introduce each cell membrane modification technique, such as gene transfer, chemical modification, and use of lipophilic anchors, and then present studies in which the kinetics of therapeutic cells were controlled by cell membrane modification using these techniques. Finally, we will also introduce our work on orientation-aligned modification of cell membranes with a small antibody as a target-directed molecule.