학술논문

A CASE OF HYPERSENSITIVITY REACTION TO ENOKITAKE (FLAMMULINA VELUTIPES) INGESTION / 新規エノキタケアレルゲンによる即時型アレルギーの1例
Document Type
Journal Article
Source
アレルギー / Japanese Journal of Allergology. 2017, 66(10):1240
Subject
enokitake (Flammulina velutipes)
mushroom allergy
western blotting
Language
Japanese
ISSN
0021-4884
1347-7935
Abstract
We experienced a case of 10-year-old girl who developed hypersensitivity reactions after eating enokitake. The patient had food allergy to egg until 5 years old. When she was 4 years old, she ate enokitake with a hot-pot dish. Later, she felt itching in her mouth. Therefore, she never ate enokitake since that time. At the age of 10, she drank only the soup of enokitake with school lunch. After that she felt discomfort and itching in her oral cavity. The result of enokitake and other mushrooms (siitake, simeji, and eringi) skin prick to prick test were all positive. We performed Western blotting with enokitake extracts and the patient's serum. Enokitake protein's band (75kDa) reacted specifically with the patient's IgE. At the same time Western blotting was performed with the patient's serum of previously reported enokitake anaphylaxis, but a 75kDa band showing specific reaction in this case was not observed. This band we identified was a novel enokitake allergen.