학술논문
Association of Left Atrial Size With Stroke or Systemic Embolism in Patients With Atrial Fibrillation Having Undergone Bioprosthetic Valve Replacement From the BPV-AF Registry
Document Type
Journal Article
Author
Chisato Izumi; Hidekazu Tanaka; Hiroya Kawai; Kenichi Tsujita; Kenji Ando; Kenji Minatoya; Kiyoshi Yoshida; Kiyoyuki Eishi; Kunihiro Nishimura; Makoto Miyake; Masaki Izumo; Masashi Amano; Misa Takegami; Ryuzo Nawada; Tadaaki Koyama; Takeshi Kimura; Takeshi Kitai; Tatsuhiko Komiya; Tetsuya Kimura; Tomohiro Sakamoto; Tomoyuki Fujita; Toshihiro Fukui; Yasushi Sakata; Yoshisato Shibata; Yutaka Furukawa; for the BPV-AF Registry Group
Source
Circulation Reports. 2023, 5(5):210
Subject
Language
English
ISSN
2434-0790
Abstract
Methods and Results: Of 894 patients from a previous multicenter prospective observational registry (BPV-AF Registry), 533 whose LAVI data had been obtained by transthoracic echocardiography were included in this subanalysis. Patients were divided into tertiles (T1–T3) according to LAVI as follows: T1 (n=177), LAVI=21.5–55.3 mL/m2; T2 (n=178), LAVI=55.6–82.1 mL/m2; T3 (n=178), LAVI=82.5–408.0 mL/m2. The primary outcome was defined as either stroke or systemic embolism for a mean (±SD) follow-up period of 15.3±4.2 months. Kaplan-Meier curves indicated that the primary outcome tended to occur more frequently in the group with the larger LAVI (log-rank P=0.098). Comparison of T1 with T2 plus T3 using Kaplan-Meier curves indicated that patients in T1 experienced significantly fewer primary outcomes (log-rank P=0.028). Furthermore, univariate Cox proportional hazard regression showed that 1.3- and 3.3-fold more primary outcomes occurred in T2 and T3, respectively, than in T1.