학술논문

Effects of Medications Involved in Constipation on the Severity of Colonic Diverticulitis / 便秘に関与する薬剤が大腸憩室炎の重症度に及ぼす影響
Document Type
Journal Article
Source
日本大腸肛門病学会雑誌 / Nippon Daicho Komonbyo Gakkai Zasshi. 2023, 76(1):8
Subject
complicated diverticulitis
laxatives
psychotropic drugs
便秘薬
向精神薬
膿瘍や穿孔を伴った大腸憩室炎
Language
Japanese
ISSN
0047-1801
1882-9619
Abstract
Results: Multivariate analysis showed that psychotropic drugs were the factor that increased complicated diverticulitis (odds ratio 6.55, 95% confidence interval 1.84-23.40), and laxatives were the factor that decreased complicated diverticulitis (odds ratio 0.12, 95% confidence interval 0.04-0.41). The combined use of psychotropic drugs and laxatives reduced the incidence of complicated diverticulitis from 77.8% to 44.0% compared to non-combination (P=0.034). Among laxatives, the incidence of complicated diverticulitis decreased when probiotics were used in combination (P=0.025).