학술논문
Prognostic Factors in Patients with Peritonitis Caused by Perforation of the Left Hemicolon Treated by Emergency Surgery ─ Application and Effects of Direct Hemoperfusion with Polymyxin B-immobilized Fiber（PMX-DHP） / 左側大腸穿孔による腹膜炎に対して緊急手術を施行した症例の予後因子の検討 ～Direct Hemoperfusion with Polymyxin B-immobilized Fiber（PMX-DHP）の適応と効果について～
Document Type
Journal Article
Author
Source
日本腹部救急医学会雑誌 / Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine). 2021, 41(1):23
Subject
Language
Japanese
ISSN
1340-2242
1882-4781
1882-4781
Abstract
We examined the prognostic factors in patients with peritonitis caused by perforation of the left hemicolon who underwent emergency surgery at our hospital. The subjects were 59 patients aged 78 years old（median）and 10（16.9%）of the patients died. Significant poor prognostic factors included preoperative shock, preoperative leukopenia, preoperative base excess（BE）, and preoperative sequential organ failure assessment（SOFA）score. Direct hemoperfusion with polymyxin B-immobilized fiber（PMX-DHP）was performed, especially for serious patients. Subgroup analysis of the above 4 poor prognostic factor groups and the Hinchey stage Ⅳ group was performed to evaluate whether PMX-DHP contributed towards the prognosis. We could not show any beneficial effect on the prognosis of PMX-DHP in any of the subgroups（groups with preoperative shock, preoperative leukopenia, lower preoperative BE, higher preoperative SOFA score, and Hinchey stage Ⅳ）.