학술논문

Rhabdomyolysis, Acute Renal Failure and Hepatopathy Induced by Lovastatin Monotherapy
Document Type
Journal Article
Source
Japanese Heart Journal. 1997, 38(4):541
Subject
Acute renal failure
Lovastatin
Rhabdomyolysis
Language
English
ISSN
0021-4868
1348-673X
Abstract
Lovastatin is a popular drug for the treatment of hypercholesterolemia. Few serious complications are associated with its use although rhabdomyolysis with renal failure has been reported when lovastatin is combined with cyclosporine or other drugs following transplantation. We report the case of a patient who developed hepatopathy and rhabdomyolysis accompanied by acute renal failure after 4 weeks of lovastatin monotherapy. The pathogenesis and treatment of these complications are also discussed.