부산대학교 도서관

A case of intraductal apocrine carcinoma of the breast in a 78-year-old woman is reported herein. Our patient presented with a small, elastic and hard mass with ill-defined margin, measuring 0.8cm, in the upper outer quadrant (C area) of the right breast. Since mammography and ultsanonography suggested mastopathy, the patient was scheduled for follow-up. A follow-up routine check did not show any changes until 8 years had elapsed after the first visiting, when aspiration biopsy cytology offered a suspicion of breast carcinoma. Excisional biopsy was carried out. Almost of the tumor cells showed apocrine metaplasia without invasion into the stroma. And the tumor was diagnosed as intraductal apocrine carcinoma. Modified radical mastectomy was performed due to intraductal spreading. Apocrine carcinoma accounts for about 0.2%, of all breast cancers. It is histopathological classified only into invasive carcinoma, and no description on intraductal apocrine carcinoma exist is found in the General Rules for Clinical and Pathological Recording of Breast Cancer, the Japanese Breast Cancer Society. This case is a rare case that was diagnosed as intraductal apocrine carcinoma, and so far 15 cases of intraductal apocrine of the breast, including this case, have been reported in the Japanese literature. Therefore, the general rules of clinicopathology of the disease should be classified as noninvasive ductal carcinoma, apocrine type “intraductal apocrine carcinoma” in the near future.