학술논문

rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome
Document Type
Journal Article
Source
Internal Medicine. 2017, 56(4):441
Subject
branch atheromatous disease
capsular warning syndrome
thrombolysis
Language
English
ISSN
0918-2918
1349-7235
Abstract
We herein report a case of capsular warning syndrome (CWS) that was successfully treated with recombinant tissue plasminogen activator (rt-PA). A 70-year-old woman had repeated stereotyped transient ischemic attacks (TIAs) of right hemiparesis and dysarthria. After hospitalization, argatroban, aspirin, and cilostazol were started but were ineffective. Thirteen hours after the first episode of TIAs, severe symptoms occurred. Magnetic resonance imaging showed acute infarctions in the internal capsule to corona radiata, so we used rt-PA. Since then, the TIAs have not occurred, and the symptoms have considerably improved. This case suggests that rt-PA might be effective and safe for use in treating CWS.