학술논문

A Case of Recurrent Bacterial Meningitis in a Girl with Mondini Deformity / 反復する細菌性髄膜炎の管理に難渋したMondini奇形
Document Type
Journal Article
Source
日本医科大学医学会雑誌 / Nihon Ika Daigaku Igakkai Zasshi. 2022, 18(3):299
Subject
24F
Mondini deformity
invasive pneumococcal disease
recurrent bacterial meningitis
Language
Japanese
ISSN
1349-8975
1880-2877
Abstract
Delayed diagnosis of bacterial meningitis has a significant impact on prognosis and should not be overlooked. Cases of recurrent bacterial meningitis in infancy may be associated with underlying diseases such as immunodeficiencies and congenital deformities, including those of the inner ear. Streptococcus pneumoniae is a highly invasive causative agent, but the number of patients with meningitis has decreased dramatically in recent years due to the widespread use of the 13-valent pneumococcal conjugate vaccine. However, cases of vaccinated patients having invasive pneumococcal infection have been reported due to serotypes changing. We report a case of recurrent bacterial meningitis in an infant. The second occurrence was associated with Mondini deformity, for which surgical treatment was planned. The third was observed while the patient was awaiting surgery, and the fourth postoperatively. This study presents the clinical course of the Mondini deformity in this patient, which was difficult to manage due to the recurrent bacterial meningitis, and draws on epidemiological data concerning invasive pneumococcal infections occurring between April 2013 and March 2021 in Kawasaki City, Kanagawa Prefecture, Japan.