부산대학교 도서관

In 94 coal miners whose chest X-ray classification indicated type P1 to Type C pneumoconiosis, comparative studies on selective alveolo-bronchography (SAB) findings and pulmonary function tests were carried out. Controls consisted of 26 individuals without symptomatic pulmonary disease. Results were as follows.1. Of 94 pneumoconiosis cases 41 had pulmonary emphysema as a complication (43.6%). This percentage was definitely higher than that of the control group which had pulmonary emphysema in 15.4 per cent. The emphysema which was seen in coal miners pneumoconiosis was centrilobular type in 51.2%, panacinar type in 34.1% and mixed type in 14.6%.2. Findings of chronic inflammation in the bronchi, recognized on SAB, were seen in 83.7 per cent of pneumoconiosis cases.3. Even in early stage pneumoconiosis by X-ray classification, emphysematous changes were proved to be present.4. Emphysematous changes were observed in 50.0% of cases with severely damaged bronchi, in 43.2% of cases with mildly damaged bronchi and in 33.3% of cases with normal bronchi. These findings suggested that bronchial damage was an important factor in the development of emphysema in coal miners.5. The degree of damage in bronchi and alveoli as shown on SAB showed a tendency to correlate with that of incompetency on the pulmonary function test. Statistical studies by multiple regression analysis showed that stenosis at bifurcations, irregularity of the bronchial wall and spastic narrowing of bronchi and emphysematous changes of the alveoli were related to lowering of the values of FEV1.0/pred. VC and V25/Ht.6. SAB was useful for the early diagnosis of bronchial damage and emphysematous changes in alveoli which affect the pulmonary function in pneumoconiosis.