학술논문

Treatment Experience of Two Cases of Primary Cutaneous Adenoid Cystic Carcinoma / 皮膚原発腺様囊胞癌2例の治療経験
Document Type
Journal Article
Source
日本医科大学医学会雑誌 / Nihon Ika Daigaku Igakkai Zasshi. 2018, 14(1):25
Subject
cribriform pattern
local recurrence
neuronal invasion
primary cutaneous adenoid cystic carcinoma
Language
Japanese
ISSN
1349-8975
1880-2877
Abstract
Primary cutaneous adenoid cystic carcinomas (ACCs) are rare. We report two cases of the primary cutaneous ACC. We resected dorsal crimson nodule in case 1 and resected crimson nodule of the back of the left side of head in case 2. Histopathological evaluation showed that luminal structure was formed of lumen epithelial cells and myoepithelial cells. The structure gathered and formed a cribriform pattern. Additionally, neuronal invasion was noted. No other obvious primary lesions were detected during the systemic examination. According to these findings, we therefore diagnosed this tumor as a primary cutaneous adenoid cystic carcinoma. Resection with an approximately 30 mm margin in both cases was performed. Local recurrence and metastasis are not detected now. ACC often shows neuronal invasion and local recurrence. Therefore, extended resection and a long-term follow-up are needed. When a skin tumor is examined, ACC should always be taken into consideration.