부산대학교 도서관

A total of 204 patients with vertigo or dizziness were examined using N-isopropylp-(I-123) iodoamphetamine (IMP) and single photon emission computed tomography (SPECT) and the findings were compared to X-ray CT and magnetic resonance imaging (MRI) findings. SPECT was performed using a rotating gamma camera. Decreased IMP in the cerebellum and brain stem was observed in 123/204 (60.3%) studies of these patients. Of these 123 patients, 98 were diagnosed as having a vascular disorder. All 98 patients were examined by X-ray CT and only 12 patients (12/98, 12.2%) showed vascular lesions by X-ray CT. Of the 98 patients, 26 were assessed by MRI and 8 patients (8/26, 30.8%) showed vascular lesions.Our findings showed that most patients with vertigo or dizziness of so-called vertebro-basilar insufficiency (VBI) may have some vertebral blood flow disorder, which in some cases is not clearly diagnosed by conventional vestibular examinations, X-ray CT or MRI.SPECT with IMP would likely be useful to evaluate abnormal cerebellar and brain stem perfusion.