부산대학교 도서관

A 61-year-old female having undergone radical mastectomy 4 years previously was readmitted because of dyspnea. Chest X-ray and CT scan revealed multiple metastatic pleural nodules and effusion. The patient had thrombocytopenia and leukopenia due to liver cirrhosis and was treated with a combined chemoendocrine therapy consisted of epirubicin, mitomycin C, UFT, tamoxifen and medroxyprogesterone acetate. The patient lost her consciousness temporarily with respiratory acidosis but emerged 5 days later. Six months after the introduction of the therapy the metastatic nodues completely disappeared on chest X-ray and CT scan. Her performance status improved markedly and the duration of a complete response has lasted 21 months to this day.