학술논문

A Case of Mucosal Prolapse Syndrome (MPS) with Well-Differentiated Adenocarcinoma / 高分化型腺癌を合併した直腸粘膜脱症候群(MPS:Mucosal Prolapse Syndrome)の1例
Document Type
Journal Article
Source
日本大腸肛門病学会雑誌 / Nippon Daicho Komonbyo Gakkai Zasshi. 2014, 67(4):268
Subject
悪性腫瘍
直腸粘膜脱症候群
Language
Japanese
ISSN
0047-1801
1882-9619
Abstract
In May 2010, a 38-year-old woman visited a local hospital for evaluation of occult blood in stool, mild anemia and anal bleeding after defecation. As colonoscopy demonstrated serrated polyps at the dentate line, she was referred to our hospital for further evaluation and treatment. The physical examination was unremarkable except for the rectal examination, during which a soft tumor was palpated. As she also had had a “straining” habit for more than ten years, local excision of the lesions was performed with the diagnosis of mucosal prolapse syndrome (MPS). Histopathologically, the rectal mucosa of these lesions exhibited fibromuscular obliteration within the lamina propria, which is characteristic of MPS. Furthermore, a part of one of the two lesions, 11mm in diameter, demonstrated well differentiated adenocarcinoma accompanied by high-grade tubular adenoma. She has been followed for 3 years without any evidence of recurrence.