학술논문

Acute stroke in patients with COVID-19: a single-center, retrospective, observational study / COVID-19感染症拠点病院における,脳卒中を合併した症例の後方視的検討
Document Type
Journal Article
Source
脳卒中 / Japanese Journal of Stroke. 2023, 45(1):8
Subject
COVID-19
risk factors
stroke
Language
Japanese
ISSN
0912-0726
1883-1923
Abstract
Background and Purpose: New-onset stroke has been observed in patients with coronavirus disease 2019 (COVID-19). The aim of this study was to investigate the characteristics of new-onset stroke in patients with COVID-19. Methods: We retrospectively investigated the clinical characteristics, laboratory findings on admission, and outcomes in 1101 patients with COVID-19 who were admitted to our hospital between March 1, 2020, and September 30, 2021, according to whether or not they developed stroke. Results: Eight patients developed acute ischemic stroke and one had an intracerebral hemorrhage. Patients with COVID-19 who developed stroke were significantly older than those who did not and had pre-existing cardiovascular risk factors, including hypertension, diabetes, and chronic renal failure. There was a significant correlation between severity of COVID-19 and new-onset stroke. Mortality was higher in the group with stroke. Laboratory values on admission indicated a significant inflammatory response and an elevated D-dimer level. Conclusion: We have investigated the characteristics and risk factors of new-onset stroke in patients with COVID-19. More research is needed on how to prevent, diagnose, and treat new-onset stroke in patients with COVID-19.