학술논문
Growth-promoting Effects of an Extract of a Thermophilic Blue-green Alga, Synechococcus elongatus var. on Human Cell Lines
Document Type
Journal Article
Source
Agricultural and Biological Chemistry. 1986, 50(9):2225
Subject
Language
English
ISSN
0002-1369
1881-1280
1881-1280
Abstract
The growth-promoting effects of a dialyzate of the extract from a thermophilic blue-green alga, Synechococcus elongatus var. on several humal cell lines were studied in serum-free media. The dialyzate promoted the growth of RPMI 8226 (a myeloma cell line), Molt-4 (an acute T-lymphatic leukemia cell line), and HMY-2 and HO-323 (B-lymphoblastoid cell lines). The supplementation of basal RDF medium with the dialyzate enhanced the growth of HMY-2, HO-323, and RPMI 8226 cells more than that with a mixture of insulin, transferrin, ethanolamine, and selenite. Culture of RPMI 8226 cells for 2 weeks was achieved by use of the dialyzate-supplemented RDF medium. The growth-promoting activity of the dialyzate was heat-stable.