학술논문

A Case of Conversion Hepatectomy for Hepatocellular Carcinoma with Vp4 Portal Vein Tumor Thrombosis after Lenvatinib Therapy / レンバチニブ投与後根治的肝切除を行ったVp4肝細胞癌の1例
Document Type
Journal Article
Source
日本臨床外科学会雑誌 / Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 2022, 83(10):1787
Subject
hepatectomy
hepatocellular carcinoma
portal vein tumor thrombosis
肝切除
肝細胞癌
門脈腫瘍栓
Language
Japanese
ISSN
1345-2843
1882-5133
Abstract
A 70-year-old man was referred to our hospital with a diagnosis of ruptured hepatocellular carcinoma in segment 4 of the liver and transcatheter arterial embolization (TAE) was subsequently carried out on an emergency basis. At that time a contrast-enhanced CT scan revealed a portal vein thrombus (Vp4) from the left branch to the main trunk. Systemic chemotherapy was selected, and we started treatment with lenvatinib (12mg/day) in December 2019. The tumor responded well to the 6-week treatment, CT showed shrinkage of both the tumor and portal vein thrombus, and conversion surgery was decided. Laparoscopic left hepatectomy was performed in February 2020. Intraoperatively, the left portal vein was divided after the absence of tumor thrombus was confirmed with intraoperative ultrasonography. The postoperative course was uneventful and the patient has been alive for 2 years postoperatively without recurrence.