부산대학교 도서관

A 70-year-old man was referred to our department because of a fever of over 39℃, a sore throat, and skin eruptions for several months. We initially suspected a serious infection due to acute pharyngitis and laryngitis because many aphthous ulcers were found in his oral cavity, pharynx, and larynx. The pharyngeal and laryngeal findings were almost completely improved by intravenous antibiotic treatment, and the skin eruptions tended to disappear, but a slight elevation of inflammatory marker, remittent fever, and macrocytic anemia continued. In addition, new skin eruptions appeared on his chest, back, and both upper limbs 21 days after admission. Therefore, we performed a skin and bone marrow biopsy to scrutinize the new skin eruptions and anemia. As a result of this biopsy, he was diagnosed as Sweet’s syndrome associated with myelodysplastic syndrome （MDS）. In cases of acute pharyngitis and laryngitis with skin eruptions, if the symptoms persist even after antibiotic treatment, there may be Sweet’s syndrome or autoimmune disease in the background.