학술논문

Analysis of the relationship between SCC antigen in maternal blood during pregnancy, and SCC antigen in amniotic fluid, and the amount of bleeding during delivery / 妊娠中の母体血中SCC抗原,羊水中SCC抗原,及び,分娩時出血量の検討 ─子宮型羊水塞栓症の解明に向けて─
Document Type
Journal Article
Source
日本周産期・新生児医学会雑誌 / Journal of Japan Society of Perinatal and Neonatal Medicine. 2021, 57(3):447
Subject
Amniotic fluid embolism
Postpartum hemorrhage
Squamous cell carcinoma antigen
Language
Japanese
ISSN
1348-964X
2435-4996
Abstract
Two types of amniotic fluid embolism(AFE)have been described : cardiopulmonary collapse type and disseminated intravascular coagulation(DIC)type, with the latter proposed as uterine type, and both are caused by the inflow of amniotic components into the maternal circulation. We investigated the relationship between Santigen in maternal blood during pregnancy, SCC antigen in amniotic fluid, and the amount of bleeding during delivery, which is one of the main symptom of AFE with uterine type. As a result, there were no significant changes in maternal blood SCC in pregnancy. Maternal blood SCC increased after vaginal delivery compared to cesarean section, and it was expected that the amount of amniotic fluid flowing into the mother was larger in vaginal delivery than cesarean section. It is argued that in vaginal delivery, there is no relationship between the estimated amount of amniotic fluid influx and the amount of bleeding during delivery, and it is expected that the onset of AFE with uterine type has other necessary factors besides the influx of amniotic fluid into maternal blood, such as anaphylactoid reaction.