부산대학교 도서관

In this study, we synthesized the glucose-responsive hydrogel microparticles containing phenylboronic acid units by emulsion polymerization. The diameters of hydrogel microparticles could be controlled in the range between 133 nm and 199 nm by changing the surfactant concentration in emulsion polymerization. As-prepared hydrogel microparticles showed the coefficient of variation with approximately 10% in particle diameter regardless of the difference particle diameters, implying the relative monodispersity of microparticles. When glucose was added to the aqueous suspensions of hydrogel microparticles, the visible Bragg reflection visually appeared under alkaline conditions due to the formation of colloidal crystals caused by the increase of particle diameter triggered by the binding of glucose to the particles. Since the critical glucose concentrations to show a visible Bragg reflection were dependent on the concentration or diameter of microparticles, these hydrogel microparticles can be applied to the diabetic detectors and sugar sensors.