학술논문

Introduction of molecular pathological analysis of glioblastoma after cerebellar medulloblastoma treatment / 小脳髄芽腫治療後に発生した膠芽腫の分子病理学的解析の導入
Document Type
Journal Article
Source
小児の脳神経 / Nervous System in Children. 2023, 48(1):21
Subject
EGFR
IDH-1
p53
pediatric medulloblastoma
radiation induced glioblastoma
secondary cancer
Language
Japanese
ISSN
0387-8023
2435-824X
Abstract
The number of long-term survivors of pediatric medulloblastoma has been increasing due to improved treatment options. However, secondary cancer can be an issue for long-term survivors. Of the 27 patients with cerebellar medulloblastoma treated at our institution, two developed cerebellar glioblastomas after the initial treatment at five years and 11 months and 22 years and eight months, respectively. These two cerebellar glioblastomas were clinically diagnosed as radiation-induced secondary cancer.