학술논문

Helium Administration is More Effective during Piston-Driven High-Frequency Oscillatory Ventilation than during Conventional Mechanical Ventilation: A Study with Rabbit Model
Document Type
Journal Article
Source
Journal of St. Marianna University. 2023, 14(2):93
Subject
Helium-oxygen mixture
carbon dioxide excretion
high-frequency ventilation
intermittent mandatory ventilation
pressure-controlled ventilation
Language
English
ISSN
2185-1336
2189-0277
Abstract
Results: There was a statistical significance for the differences of time points (P-value<0.000001) as well as for the interaction term (P-value<0.001). According to the post hoc tests, under HFOV, PaCO2 during administration of helium-oxygen mixture was significantly lower compared to both before and after administration. In intergroup comparison, PaCO2 during helium-oxygen inhalation under HFOV was significantly lower than that under CMV. Arterial partial pressure of oxygen/fraction of inspiratory oxygen ratio during administration under HFOV was significantly higher than that under CMV.