학술논문

Extranodal NK/T cell lymphoma, nasal type with local recurrence in the contralateral nasal cavity 15 years after initial sequential chemoradiotherapy / 初回逐次的放射線化学療法から15年後に対側鼻腔に局所再発をきたした節外性NK/T細胞リンパ腫,鼻型
Document Type
Journal Article
Source
臨床血液 / Rinsho Ketsueki. 2022, 63(3):229
Subject
Dose reduced SMILE chemotherapy
Extranodal NK/T cell lymphoma
Late relapse
Marginal recurrence
nasal type
Language
Japanese
ISSN
0485-1439
1882-0824
Abstract
A 72-year-old woman was diagnosed with extranodal NK/T cell lymphoma of the right nasal cavity and received sequential radiochemotherapy comprising focal radiotherapy and THP-COP chemotherapy. Showed a complete tumor response to the treatment; however, the tumor recurred in the contralateral right nasal cavity 15 years after the initial treatment. This was judged to be a marginal recurrence in the radiation field. After four cycles of dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide (SMILE) chemotherapy, a second complete response was achieved. It is possible that another recurrence occurs in the future, and if the lesion is localized at the time of recurrence, it may be possible to control the disease again. Careful follow-up is considered necessary.

Online Access