부산대학교 도서관

Polyurethane vascular prostheses (Thoratec Laboratories Corporation, USA) are compliant grafts. The grafts with 6mm diameters and 2cm lengths were implanted in the abdominal aorta of ten mongrel dogs. At operation heparin sodium was administered at the rate of 2mg/body weight (Kg), but after operation no other agent like anticoagulant was taken. Three to ten weeks after the implantation, these grafts were easily removed. All grafts were patent. Samples of extracted grafts were submitted for scanning electron micrographic and routine microscopic examinations. Spindle-shaped endothelial cells were observed all over the grafts. Beneath the layer, there were some fibrous tissue near the anastomoses, and a few fine elastic fibers could be observed within these connective tissue. In conclusion, polyurethane vascular prostheses could be available for vascular reconstruction.