학술논문
Feasibility of the method to evaluate cardiac function for doxorubicin-induced cardiotoxicity / ドキソルビシン心毒性に対する定期的な心機能評価法の有用性に関する検討
Document Type
Journal Article
Author
Source
日本婦人科腫瘍学会雑誌 / Japanese Journal of Gynecological Oncology. 2023, 41(2):227
Subject
Language
Japanese
ISSN
1347-8559
2436-8156
2436-8156
Abstract
Results: Cardiotoxicity was diagnosed in 7/144 (4.9%) of the pre-introduction group and 8/57 (14.0%) of the post-introduction group. The number of asymptomatic cardiotoxicity cases diagnosed from decreased ejection fraction by echocardiography was 2/7 (28.6%) in the pre-introduction group, significantly lower than 7/8 (87.5%) in the post-introduction group (p=0.041). Median ejection fractions after treatment for cardiotoxicity were 38%in the pre-introduction group and 54%in the post-induction group, being significantly higher in the post-induction group (p=0.028).