학술논문

HLA-DRB1 Is Associated with Therapeutic Responsiveness in IgG4-related Disease
Document Type
Journal Article
Source
Internal Medicine. 2024, 63(2):207
Subject
IgG4-related disease
glucocorticoid
human leucocyte antigen
relapse
valine
Language
English
ISSN
0918-2918
1349-7235
Abstract
Results The DQB1*12:01 genotypes were associated with a prednisolone maintenance dose of <7 mg/day. A prednisolone dose ≥10 mg with a minimum serum IgG4 level was significantly more common in B*40:01 and DRB1-GB-7-Val (DRB1*04:01, *04:03, *04:05, *04:06, and *04:10) patients than other alleles. Relapse also tended to be more common in DRB1-GB-7-Val carriers than other alleles.