학술논문
Adiponectin Receptor gene Polymorphisms are Associated with Kidney Function in Elderly Japanese Populations
Document Type
Journal Article
Author
Source
Journal of Atherosclerosis and Thrombosis. 2019, 26(4):328
Subject
Language
English
ISSN
1340-3478
1880-3873
1880-3873
Abstract
Results: In a cross-sectional analysis at baseline, we found a significant association between the AdipoR2 SNP rs12230440 and kidney function; eGFRcys tended to increase as the number of carriers of T alleles increased after adjustment for covariates and Bonferroni correction, although the association of the SNP and annual eGFR decline could not be identified in the longitudinal data. Regarding the variants rs16850797, rs11061925, and rs10773983, each of the allele G, allele C, and allele G showed nominally significant associations with higher eGFRcys. However, this failed to reach significance after Bonferroni correction.