학술논문

Megakaryocytes detected in fine-needle aspiration cytology of the thyroid —A potential diagnostic pitfall— / 甲状腺穿刺検体中に出現した骨髄巨核球
Document Type
Journal Article
Source
日本臨床細胞学会雑誌 / The Journal of the Japanese Society of Clinical Cytology. 2020, 59(3):152
Subject
Language
Japanese
ISSN
0387-1193
1882-7233
Abstract
We present a case of goiter with ectopic bone formation and extramedullary hematopoiesis in the thyroid, diagnosed by fine-needle aspiration cytology (FNAC). A 43-year-old female patient with a calcified thyroid nodule underwent ultrasound (US) -guided FNAC. Microscopic examination showed mature megakaryocytes with multilobulated nuclei and abundant granular cytoplasm, and myeloid and erythroid cells in various stages of development in a background of benign thyroid follicular epithelial cells. Adipose tissue and fragmented bone materials were also found. Presence of hematopoietic cells in the thyroid gland is an unusual finding ; moreover, detection of giant cells in FNAC of the thyroid could lead to the mistaken diagnosis of thyroid anaplastic carcinoma.

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