학술논문

A Case of Scratched Infection by Capnocytophaga canimorsus Diagnosed Early with Microscopic Peripheral Blood Smear Examination / 末梢血液鏡検を契機として早期診断に至ったCapnocytophaga canimorsusによる掻傷感染症の1例
Document Type
Journal Article
Source
日本農村医学会雑誌 / JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE. 2016, 65(4):843
Subject
Capnocytophaga canimorsus
掻傷感染症
播種性血管内凝固症候群
紡錘状のグラム陰性桿菌
Language
Japanese
ISSN
0468-2513
1349-7421
Abstract
Capnocytophaga canimorsus is a spindle-shaped facultatively anaerobic Gram-negative rod in the oral cavity of dogs and cats. C. canimorsus rarely infects humans through an animal bite or scratch. However, it leads to severe sepsis once infection occurs, and the fatality rate is estimated to be up to 30%. The patient was a 56-year-old man with fatigue and fever. Sepsis with thrombocytopenia was suspected from the blood examination results. We decided to conduct microscopic examination of a non-stained peripheral blood smear and identified bacteria; therefore, Gram stain was immediately performed and spindle-shaped Gram-negative bacilli were detected. Additionally, the patient had a history of a bite and scratch by his cat. We suspected C. canimorsus infection from the microscopic examination findings and history. Moreover, we determined early that the pathogenic bacterium was C. canimorsus by blood culture. With immediate and proper treatment based on these results, we could rescue this septic patient with disseminated intravascular coagulation. Microscopic examination of non-stained peripheral blood smear is helpful for the early diagnosis of C. canimorsus infection.