학술논문

The Significance of Global End-diastolic Volume (GEDV), Intra-thoracic Blood Volume (ITBV), Extravascular Lung Water (EVLW) and Pulmonary Vascular Permeability (PVPI) Measured by the Transpulmonary Thermodilution Technique (TPTD) in Critically Ill Patients / 重症病態における肺経由動脈熱希釈法(TPTD)で計測される血管内容量(GEDV,ITBV),肺血管外水分量(EVLW),肺血管透過性指数(PVPI)の意義
Document Type
Journal Article
Source
日本臨床麻酔学会誌 / THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA. 2013, 33(2):254
Subject
Extravascular lung water (EVLW)
Hemodynamic monitoring
Pulmonary vascular permeability (PVPI)
Transpulmonary thermodilution technique (TPTD)
循環動態モニタリング
肺経由動脈熱希釈法
肺血管外水分量
肺血管透過性指数
Language
Japanese
ISSN
0285-4945
1349-9149
Abstract
The transpulmonary thermodilution technique (TPTD) is a multi-parametric advanced cardiopulmonary monitoring technique that provides important parameters required for making decisions in critically ill patients. The TPTD measures cardiac output (CO), global end-diastolic volume (GEDV), and intra-thoracic blood volume (ITBV), which are more reliable volumetric parameters of preload than filling pressures etc CVP, PAOP. Extravascular lung water (EVLW) is one of the most important parameters obtained by TPTD. The EVLW is an accurate quantitative parameter for pulmonary edema, the best pulmonary specific index of disease severity in patients with ARDS. Pulmonary vascular permeability (PVPI) is the ratio between EVLW and pulmonary blood volume, which indicates vascular wall damage. PVPI enables differentiation between cardiogenic (hydrostatic pulmonary edema) and non-cardiogenic (increased vascular permeability) pulmonary edema.