학술논문
Pharmacological studies on COPD model induced by exposure to cigarette smoke and poly(I:C) in mice / タバコ煙曝露及びpoly(I:C)点鼻投与によるマウスCOPDモデルの薬理学的検討
Document Type
Journal Article
Author
Source
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023, :1-062
Subject
Language
Japanese
ISSN
2435-4953
Abstract
Creating an animal model of pulmonary emphysema, a type of COPD, requires exposure to cigarette smoke (CS) for more than 3 months. The pulmonary emphysema model was induced by combination of CS exposure and polyinosinic-polycytidylic acid [poly(I:C)] administration for 4 weeks in mice, and the effects of anti-thymic stromal lymphopoietin (TSLP) antibody (Ab) and rolipram (Rol) were examined.