학술논문
Pathogenesis and Biomarkers of Eosinophilic Chronic Rhinosinusitis / 好酸球性副鼻腔炎の病態とバイオマーカー
Document Type
Journal Article
Author
Source
耳鼻咽喉科臨床 / Practica Oto-Rhino-Laryngologica. 2023, 116(4):289
Subject
Language
Japanese
ISSN
0032-6313
1884-4545
1884-4545
Abstract
Traditionally, peripheral blood eosinophilia and tissue eosinophilia have been used as biomarkers of eosinophilic inflammation. These biomarkers are used as diagnostic markers in the JESREC study. Charcot-Leyden crystals (CLCs), which are formed from galectin-10 released after extracellular trap cell death (ETosis) of activated eosinophils, also reflect eosinophilic inflammation.