부산대학교 도서관

We examined gender differences in the plasma glucose level during a 75-g oral glucose tolerance test (OGTT) in patients with an HbA1c of 6.0-6.4 % (n=375). Men had significantly higher plasma glucose levels than women at 4 time points during the OGTT (0, 30, 60 and 120 min after an oral glucose load [OGL]). Glucose tolerance was categorized according to the Japanese Society of Diabetes Mellitus criteria. Among patients with borderline type glucose tolerance, men had significantly higher plasma glucose levels at all time-points except 120 min post-OGL; women had significantly higher plasma glucose levels at 120 min post-OGL. The same trend, was observed in patients with normal type glucose tolerance; however, the result did not reach statistical significance. Among patients with diabetic type glucose tolerance, men had higher plasma glucose levels, than women at 120 min post-OGL-with a trend toward statistical significance (p=0.064). There were also no marked gender differences in the HbA1c values in any of the glucose tolerance conditions. The gender difference in the plasma glucose levels of patients with borderline type glucose tolerance disappeared in patients with diabetic type glucose tolerance.