학술논문
Thromboxane A 2 receptor signaling improves secondary lymphedema and promotes lymphangiogenesis / トロンボキサンA2受容体シグナルは、リンパ管新生を制御し続発性リンパ浮腫を改善する
Document Type
Journal Article
Author
Source
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022, :3-126
Subject
Language
Japanese
ISSN
2435-4953
Abstract
Objective: Secondary lymphedema commonly arises as a complication of cancer surgery and radiation treatment; however, the underlying mechanisms are poorly understood. We recently found that thromboxane A2 has pro-lymphangiogenic effects in inflamed tissues. The present study examined whether thromboxane A2 receptor (TP) signaling plays a role in increased lymphangiogenesis during secondary lymphedema.