학술논문
Effect of hyperglycemia on the cardiovascular functions in the isoflurane-anesthetized intact dogs / 高血糖が心血管系に及ぼす作用：イソフルラン麻酔犬での検討
Document Type
Journal Article
Author
Source
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021, :3-3
Subject
Language
Japanese
ISSN
2435-4953
Abstract
Results: Administration of glucose increased plasma glucose level and osmolality but decreased Na+, Cl− and glucagon concentrations, whereas it tended to increase insulin level accompanied with decreased K+ concentration. Glucose decreased peripheral vascular resistance, but increased heart rate, left ventricular contractility and cardiac output along with increased preload to the left ventricle. Glucose infusion prolonged atrioventricular nodal and intraventricular conduction time as well as ventricular repolarization period.