학술논문

CQ3 日本のIgE依存性鶏卵アレルギー患者もしくはその疑いのある者において,食物経口負荷試験は完全除去回避に有用か? / Is oral food challenge useful to avoid complete elimination in Japanese patients diagnosed with or suspected of having IgE-dependent hen's egg allergy?
Document Type
Journal Article
Source
日本小児アレルギー学会誌 / Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology. 2021, 35(5):490
Subject
hen's egg allergy
oral food challenge
systematic review
システマティックレビュー
食物経口負荷試験
鶏卵アレルギー
Language
Japanese
ISSN
0914-2649
1882-2738
Abstract
Results: Fifty-nine articles were selected in the study; all the references were case series or case studies in which OFC was compared to pre-challenge conditions. The overall negative ratio against egg OFC was 62.7%, but an additional 71.9% of OFC-positive patients could take eggs when expanded to partial elimination. Of the 4,182 cases, 1,146 showed AEs in the OFC, and two cases reached an SAE. Two reports showed an improvement in QOL and immunological changes, although the evidence was weak.

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