학술논문

Detecting the Neutralizing Antibody in Bulk-milk Whey To Investigate Prevalence of Infection with the Bovine Viral-diarrhea Virus / バルク乳中抗体の検出による牛ウイルス性下痢ウイルスの浸潤状況調査
Document Type
Journal Article
Source
日本獣医師会雑誌 / Journal of the Japan Veterinary Medical Association. 2004, 57(11):705
Subject
BVDV
eradication
virus-neutralization test
whey
ウイルス中和試験
乳清
清浄化
Language
Japanese
ISSN
0446-6454
2186-0211
Abstract
We investigated bulk milk samples form 196 herds in 2 districts of Hokkaido (151 farms from district A and 45 farms from district B) to determine the prevalence of infection with the bovine viral-diarrhea virus (BVDV). The BVDV was detected from a few area-A samples but from none of the area-B samples. The virus-neutralization test conducted to detect BVDV antibodies in bulk-milk whey showed neutralizing-antibody titers (NT) of more than 16 in 166 samples (84.7%). Epidemiological information obtained from 132 of the 166 herds showed that 64 herds (48.5%) had BVDV NT of more than 16. None of these herds, however, had histories of BVDV infection or vaccination; and no animals had been introduced into them from other farms. These results suggest that BVDV prevailed in these areas irrespective of BVDV-gene detection, although the origin of the BVDV infection remained unclear. Therefore, eradicating BVDV from dairy populations may necessitate longterm assessment of herd BVDV infection.