학술논문

Treatment of a Serotype-1 Hepatitis C Virus Infection Using Interferon-Beta in a Patient with a High RNA Titer Who Had Been Receiving Long-Term Hemodialysis Therapy
Document Type
Journal Article
Source
Internal Medicine. 2011, 50(7):733
Subject
depression
hemodialysis
hepatitis C virus
interferon beta
Language
English
ISSN
0918-2918
1349-7235
Abstract
A serotype-1 hepatitis C virus (HCV) infection in a 67-year-old hemodialysis patient was treated using interferon (IFN)-beta. Although the patient had a high RNA titer (5.1 log IU/mL) and had been receiving long-term hemodialysis therapy (30 years), the initial 4-week IFN-beta administration enabled a rapid virological response without any major adverse effects. However, the final outcome after 24 weeks of IFN beta treatment was classified as unchanged based on the criteria of the Conference on Intractable Hepatitis. Here, we describe our experience treating HCV infection using IFN-beta and discuss the indications for such therapy.