학술논문

ATP負荷99mTc-MIBIによる心筋血流と心機能の同時評価 / Simultaneous Assessment of Myocardial Perfusion and Left Ventricular Function at Rest and during ATP Infusion by 99mTechnetium Methoxy Isobutyl Isonitrile (MIBI)
Document Type
Journal Article
Source
RADIOISOTOPES. 1994, 43(7):405
Subject
ATP
MIBI
adenosine triphosphate
first-pass radionuclide ventriculography
myocardial perfusion
technetium-99m methoxy isobutyl isonitrile
Language
Japanese
ISSN
0033-8303
1884-4111
Abstract
First-pass radionuclide ventriculography (FRNV) followed by myocardial SPECT with99mTc-MIBI was performed on 9 patients with coronary artery disease at rest and ATP infusion. When99mTc-MIBI (740 MBq) was injected, FRNV was simultaneously performed and left ventricular function was evaluated. One hour after the injection of99mTc-MIBI, myocardial SPECT was performed. Agreements in findings with regard to the presence or absence of myocardial ischemia or infarction were 19 out of 27 (70%) segments. Left ventricular ejection fraction (LVEF) decreased (p<0.01) in the patients with multi vessel disease during ATP infusion. The wall motion abnormality during ATP infusion showed improvement after coronary bypass surgery (CABG) . Improvement of regional wall motion or LVEF (regional EF) may reflect post CABG improvement.