학술논문
Alteration in the activities of blood coagulation factors of human plasma exposed to the surfaces of synthetic materials -The effect of fillers on the blood coagulability / 合成高分子素材の血液凝固因子活性におよぼす影響
Document Type
Journal Article
Author
Source
人工臓器 / Jinko Zoki. 1982, 11(3):783
Subject
Language
Japanese
ISSN
0300-0818
1883-6097
1883-6097
Abstract
Jpn. J. Artif. Organs 11 (3), 783-785 (1982) For the purpose of the development of antithromboresistant polymers, factor assays of human citrated plasma following incubation with the surfaces of fillers such as bismuth trioxide, barium sulfate, titanium dioxide, calcium carbonate, aluminum oxide, silicon dioxide, trilead teroxide and stannic oxide were performed in high surface area-plasma volume ratios. Despite a wide variety, the activity of blood coagulation factor showed a marked siginificant pattern of reduction. Therefore, use of fillers for the antithrombogenic synthetics must be selected, taking account of the above-mentioned interaction with blood coagulation factors.