부산대학교 도서관

We describe herein a case of colon cancer developed metachronous solitary splenic metastasis after sigmoidectomy which was treated by splenectomy.A 79-year-old man underwent laparoscopic sigmoidectomy for sigmoid colon cancer. The histological diagnosis was moderately differentiated adenocarcinoma, Stage IIIa (ss, ly1, v0, n1), according to the Japanese Classification of Colorectal Carcinoma. As postoperative adjuvant chemotherapy, 12 courses of FOLFOX were carried out. Nineteen months after the surgical resection, the serum CEA level was elevated to 7.9ng/ml and a splenic tumor 18mm in diameter was revealed by abdominal CT scan. FDG-PET revealed abnormal uptake of FDG at the tumor and no other lesions were discovered. We suspected metachronous solitary splenic metastasis, and performed a splenectomy. Pathohistological findings and immunostaining method confirmed splenic metastasis from sigmoid colon cancer. Postoperative cerum CEA levels were decreased to normal level.Reported cases of solitary splenic metastasis from colon cancer are very rare, but it is considered to be one form of distant metastasis. Further studies of the multidisciplinary treatment for the disease are required.