부산대학교 도서관

2298 strains of group A streptococci isolated from patients with scarlet fever or pharyngitis at an outpatient clinic in Matsuyama City, during the 10-year period from 1975 to 1984, were examined by means of T typing, M typing, Opacity Factor (OF) test and by measuring MIC of PC G, AMPC, CEX, TC and EM. The results were as follows:1) The T type number did not necessarily correspond to the same M type number. The results of T typing did not correspond to the results of M typing in 5% of T type 1 and 4 strains, and in 20% of T type 12 strains.2) 30% of the “T type 12, M untypable” strains were OF test positive, suggesting that they belong to an M type other than 12.3) Immune serum against Matsuyama 2166 strain (T type 12-28 complex, M untypable) had a specific M antibody to Matsuyama 2166 strain but reacted neither to M 12 nor to M 28 strain.4) All of the isolates were sensitive to PC G, AMPC and CEX. T type 4 strains were resistant to TC and T type 12 strains were resistant to TC or both TC and EM.5) M type 12 strains were resistant to EM until 1982 when the isolation rate of M 12 strains was the least, and were replaced from 1983 by EM sensitive M 12 strains, which have been increasingly isolated thereafter.It was concluded from these results that the type-prevalence of Group A streptococci based on the T typing method should be carefully reappraised by means of additional tests, such as the opacity factor test, and preferably by means of M typing.